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Activation of PKC supports the anticancer activity of tigilanol tiglate and related epoxytiglianes - Scientific Reports
The long-standing perception of Protein Kinase C (PKC) as a family of oncoproteins has increasingly been challenged by evidence that some PKC isoforms may act as tumor suppressors. To explore the hypothesis that activation, rather than inhibition, of these isoforms is critical for anticancer...
www.nature.com
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